Related Experiment Video
Updated: Aug 17, 2026

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
Published on: September 26, 2020
[Modified Komeda-David operation for postinfarction ventricular septal perforation]
Noriyasu Kawada1, H Kurosawa, K Suzuki
1Department of Cardiac Surgery, Jikei University School of Medicine, Tokyo, Japan.
Abstract:
The infarct exclusion technique with a xeno-pericardial patch which Komeda and associates firstly reported in 1990 is one of the best procedure to close ventricular septal perforation. A large patch can protect the perforation and the surrounding weak tissue from the internal left ventricular pressure. However, suturing this large patch to the left ventricular wall through the small incision is not technically easy because of the patch design in the ventricle. We modified the design of the patch. This round shaped bovine pericardial patch was sutured continuously to the left ventricular wall. Then, excessive part of the patch was trimmed to make a corn shape. Finally, the corn shaped patch fit the left ventricular wall naturally.
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