Related Experiment Video
Updated: Aug 18, 2026

Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model
Published on: February 7, 2025
[Marrow stromal cells and repair of bone defect]
Songlin Peng1, Huang Fang, Yongxiang Luo
1Department of Orthopaedics, Tongji Hospital, Tongji Medical College of Huazhong Science and Technology University, Wuhan Hubei 430030, PR China.
Objective:
To review researches on the relation between marrow stromal cells (MSCs) and repair of bone defect.
Methods:
The latest original literatures about marrow stromal cells and their use in the treatment of bone defect were extensively reviewed.
Results:
Marrow stromal cells were induced to osteoblasts under proper conditions and showed the potential of bone formation in vivo. The methods of bone tissue engineering using MSCs as seed cells and gene therapy using MSCs as target cells were both useful in the repair of bone defect.
Conclusion:
MSCs have a promising future in the repair of bone defect.
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