Related Experiment Video
Updated: Aug 18, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Recurring methicillin-resistant Staphylococcus aureus infections in a football team
Dao M Nguyen1, Laurene Mascola, Elizabeth Brancoft
1Los Angeles County Department of Health Services, Los Angeles, California 90012, USA. daonguyen@ladhs.org
Abstract:
An outbreak of community-associated methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infection (SSTI) occurred in a college football team from August to September 2003. Eleven case-players were identified, and boils were the most common sign. Linemen had the highest attack rate (18%). Among 99 (93% of team) players with cultured specimens, 8 (8%) had positive MRSA nasal cultures. All available case-players' MRSA isolates characterized had the community-associated pulsed-field type USA300. A case-control study found that sharing bars of soap and having preexisting cuts or abrasions were associated with infection. A carrier-control study found that having a locker near a teammate with an SSTI, sharing towels, and living on campus were associated with nasal carriage. Successful outbreak control measures included daily hexachlorophene showers and hygiene education.
Insights
Community-associated methicillin-resistant Staphylococcus aureus (MRSA) caused skin infections in a college football team. Sharing soap and having cuts increased infection risk, while hygiene education helped control the outbreak.
Area of Science:
- Infectious Diseases
- Public Health
- Epidemiology
Background:
- Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) outbreaks pose risks in close-contact settings.
- Skin and soft tissue infections (SSTIs) are common manifestations of MRSA.
Purpose of the Study:
- To investigate an outbreak of MRSA SSTI in a college football team.
- To identify risk factors for infection and nasal carriage.
- To evaluate control measures.
Main Methods:
- Descriptive epidemiology of the outbreak.
- Case-control and carrier-control studies.
- Laboratory characterization of MRSA isolates (pulsed-field gel electrophoresis).
Main Results:
- Eleven MRSA SSTI cases were identified, with boils as the most common sign.
- Linemen had the highest attack rate (18%).
- Sharing soap and pre-existing skin abrasions were associated with infection; locker proximity, towel sharing, and on-campus living were linked to nasal carriage.
- All isolates were identified as the community-associated pulsed-field type USA300.
Conclusions:
- Close-contact sports teams are vulnerable to MRSA SSTI outbreaks.
- Personal hygiene practices and environmental factors play a significant role in transmission.
- Targeted hygiene interventions, such as daily antiseptic showers and education, can effectively control MRSA outbreaks.
Related Concept Videos
Staphylococcal Skin Infections
Clinical Significance of Antibiotic Resistance
Mechanism of Antibiotic Resistance in MRSA
Endocarditis III: Medical Management
Endocarditis I: Introduction
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
