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High-performance liquid chromatographic determination of ciprofloxacin in plasma
A C Mehta1, S Hart-Davies, E A Kay
1Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K.
Journal of Clinical Pharmacy and Therapeutics
|April 1, 1992
Abstract:
This paper describes an accurate, specific and sensitive high-performance liquid chromatographic (HPLC) method for the determination of ciprofloxacin in small samples (0.5 ml). The samples, after pretreatment by solvent extraction, were eluted on a reversed-phase column and detected by an ultraviolet detector. The results obtained on patient samples are presented.