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Actinic prurigo: clinical features and prognosis
P R Lane1, D J Hogan, M J Martel
1Division of Dermatology, University of Saskatchewan, Saskatoon, Canada.
Journal of the American Academy of Dermatology
|May 1, 1992
Summary
Actinic prurigo in Amerindians is often hereditary, affecting the face and causing itching. Younger onset (under 20) generally leads to better prognosis than adult onset.
Area of Science:
- Dermatology
- Photodermatology
- Genetics
Background:
- Actinic prurigo is an idiopathic familial photodermatosis.
- Previously described in Amerindians across North and South America.
Purpose of the Study:
- Describe clinical features and prognosis of actinic prurigo.
- Focus on Amerindian population in Saskatchewan, Canada.
Main Methods:
- Clinical examinations
- Patient questionnaires
- Phototesting
- Laboratory tests
Main Results:
- 93 Amerindian patients studied.
- Face most commonly affected; hereditary tendency, cheilitis, and pruritus are prominent.
- Majority sensitive to ultraviolet A (UVA) light; 1/3 experience winter lesions.
Conclusions:
- Age of onset is key predictor of actinic prurigo type and prognosis.
- Younger onset (≤20 years) associated with cheilitis, acute eruptions, and better 5-year improvement.
- Adult onset (≥21 years) linked to milder, more persistent dermatosis.
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