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Related Experiment Videos

Caffeine increases exogenous carbohydrate oxidation during exercise.

Sophie E Yeo1, Roy L P G Jentjens, Gareth A Wallis

  • 1Human Performance Laboratory, School of Sport and Exercise Sciences, Univ. of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|April 16, 2005
PubMed
Summary

Caffeine co-ingested with glucose significantly enhances exogenous carbohydrate oxidation during prolonged exercise. This suggests caffeine may improve glucose absorption, boosting fuel utilization in athletes.

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Area of Science:

  • Exercise Physiology
  • Nutritional Biochemistry
  • Sports Science

Background:

  • Carbohydrate and caffeine are established ergogenic aids for exercise.
  • Caffeine's effect on glucose metabolism is debated, with potential impacts on intestinal absorption and muscle uptake.

Purpose of the Study:

  • To investigate the impact of caffeine co-ingestion on exogenous carbohydrate oxidation during endurance exercise.

Main Methods:

  • Eight male cyclists completed a randomized crossover trial.
  • Exercise involved 120 minutes at 64% maximal oxygen uptake.
  • Ingested treatments: glucose solution, glucose with caffeine, or water, with 13C-labeled glucose to track oxidation.

Main Results:

  • Exogenous carbohydrate oxidation was 26% higher with glucose plus caffeine compared to glucose alone (90-120 min).

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  • Total carbohydrate oxidation was highest with glucose plus caffeine ingestion.
  • A trend towards increased endogenous carbohydrate oxidation was observed with caffeine co-ingestion.

    • Conclusions:

    • Co-ingesting caffeine (5 mg/kg/h) with glucose enhances exogenous carbohydrate oxidation during prolonged cycling.
    • This enhancement is likely due to caffeine increasing intestinal glucose absorption.