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Updated: Aug 18, 2026

Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
Published on: March 10, 2020
Morphological studies in modern teratological investigations
Franciszek Burdan1, Justyna Szumiło, Jarosław Dudka
1Experimental Teratology Unit, Department of Human Anatomy, Medical University of Lublin, 20-074 Lublin, Poland. fb3@wp.pl
Abstract:
Despite the variety of modern molecular techniques available, examination of foetal anatomy is still a fundamental part of teratological studies in evaluating the developmental toxicity of xenobiotics or other non-chemical factors. The article presents contemporary methods of embryotoxicity and foetotoxicity assessment. A single alizarin red S and double alcian blue followed by alizarin red S staining, as well as various methods of soft tissue examination are discussed.
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