How and when did Arabidopsis thaliana become highly self-fertilising

Changes in breeding system are a regular evolutionary change in plants, as self-fertilisation is often advantageous, particularly for weedy and colonising species. The adoption of Arabidopsis thaliana as a plant model species has led to interest in how self-incompatibility was lost so that this species became highly inbreeding. Molecular evolutionary approaches have recently focused on investigating two loci involved in the incompatibility recognition process in related Arabidopsis species; non-functional copies of these genes still exist in A. thaliana. New work studying polymorphism at these loci found strikingly low diversity at one of them, suggesting that spread of a mutation in this gene might have caused self-compatibility in an ancestor of A. thaliana. However, it is difficult to be sure of the time when the selfing habit evolved in the lineage that led to A. thaliana.