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Drug compliance among hypertensive patients in Port Harcourt, Nigeria

M R Akpa1, D I Agomuoh, O J Odia

  • 1Department of Medicine, University of Port Harcourt Teaching Hospital, Nigeria.

Nigerian Journal of Medicine : Journal of the National Association of Resident Doctors of Nigeria
|April 19, 2005
PubMed

Insights

Good adherence to high blood pressure medication is crucial for reducing cardiovascular risks. This study found that taking one daily pill, especially with higher education, significantly improves patient compliance with antihypertensive therapy.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacology

Background:

  • Hypertension is a major risk factor for cardiovascular disease, increasing morbidity and mortality.
  • Effective blood pressure control is essential for mitigating cardiovascular complications.
  • Achieving adequate blood pressure control hinges on patient adherence to prescribed antihypertensive treatments.

Purpose of the Study:

  • To assess the level of patient compliance with antihypertensive medications.
  • To identify factors influencing adherence to hypertension treatment regimens.

Main Methods:

  • A study involving 100 patients (aged 30-79) at the University of Port Harcourt Teaching Hospital.
  • Direct patient interviews using a structured questionnaire to gather data on drug compliance.
  • Data analysis of responses to determine compliance rates based on various factors.

Main Results:

  • Overall good compliance was reported by 60% of patients, with fair compliance in 29% and poor compliance in 11%.
  • Higher educational attainment correlated with better compliance rates (67% for tertiary education vs. 41% for primary).
  • Monotherapy (one drug) showed significantly higher compliance (74%) compared to polytherapy (33% for four drugs).
  • Single daily dosing regimens resulted in better compliance (70%) than twice (55%) or thrice daily (17%) dosing.

Conclusions:

  • Antihypertensive therapy compliance is optimized with single-drug regimens (monotherapy) and simple dosing schedules.
  • Patient education plays a significant role in improving adherence to hypertension management.
  • Simplifying medication regimens can enhance treatment effectiveness and reduce cardiovascular risks.
Abstract

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