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Endobronchial non-Hodgkin's lymphoma
M S Barthwal1, R B Deoskar, J J J Falleiro
1Department of Pulmonary Medicine, Military Hospital (Cardio Thoracic Centre), Pune, India. msbarthwal@rediffmail.com
The Indian Journal of Chest Diseases & Allied Sciences
|April 19, 2005
Summary
Anaplastic large cell lymphoma, a rare non-Hodgkin's lymphoma subtype, presented as an endobronchial mass causing left lung collapse. This case highlights a unique clinical manifestation of this hematologic malignancy.
Area of Science:
- Oncology
- Pulmonology
- Hematology
Background:
- Non-Hodgkin's lymphoma (NHL) is a diverse group of lymphoid malignancies.
- Endobronchial masses typically arise from primary lung cancers or metastases.
- Intrabronchial NHL is an exceptionally rare clinical presentation.
Observation:
- A 23-year-old male presented with symptoms and imaging indicative of left lung collapse.
- Fiber-optic bronchoscopy identified a smooth, globular mass obstructing the left main bronchus.
- Biopsy confirmed the mass as anaplastic large cell lymphoma (ALCL), a subtype of NHL.
Findings:
- The endobronchial mass was diagnosed as ALCL, a rare extranodal presentation of NHL.
- The tumor's location led to significant airway obstruction and subsequent lung collapse.
- Histopathological analysis confirmed the diagnosis of ALCL.
Implications:
- This case underscores the importance of considering extranodal lymphoma in the differential diagnosis of endobronchial masses.
- Rare presentations of NHL can mimic more common pulmonary pathologies, necessitating thorough investigation.
- Highlights the need for multidisciplinary approaches in diagnosing and managing unusual oncologic emergencies.