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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
[Melanotic neurofibroma, clinical and histopathologic diagnosis. Case report]
Anca Zbranca1, Raluca Stefan, Mirela Grigorovici
1Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Bioinginerie, Disciplina de Dermatologie.
Abstract:
Melanotic neurofibroma is a rare benign tumor, derived from peripheral nerve sheath, whose originality consists in the presence of melanic pigment. The clinical diagnosis is difficult to establish, requiring the histopathological exam to make the difference between melanotic neurofibroma and the other pigmented tumors. Although, sometimes neither the anatomopathological exam can establish the final diagnosis, requiring supplementary studies. Melanotic neurofibroma has a good prognosis and the malignization is rare. The elective treatment is surgical, represented by the complete excision of the tumor.
