Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human cortical responses during one-bit delayed-response tasks: an fMRI study.

Claudio Babiloni1, Antonio Ferretti, Cosimo Del Gratta

  • 1Dipartimento di Fisiologia Umana e Farmacologia, Sezione di EEG ad Alta Risoluzione, Università degli Studi di Roma La Sapienza, P.le Aldo Moro 5, 00185 Rome, Italy. claudio.babiloni@uniroma1.it

Brain Research Bulletin
|April 19, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations of daily step counts with cognitive, clinical, and resting-state electroencephalographic measures in patients with cognitive decline due to Alzheimer's disease.

GeroScience·2026
Same author

Glymphatic clearance as revealed by diffusion tensor imaging along the perivascular space (DTI-ALPS) is associated with Alzheimer's disease neuropathology and periodic rsEEG alpha rhythms in mild cognitive impairment participants.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Abnormal periodic and aperiodic resting-state electroencephalographic markers in Lewy body and Alzheimer's diseases with cognitive decline.

GeroScience·2026
Same author

Source-space EEG alpha activity reveals brain age gaps due to neurodegeneration and disparity.

Communications biology·2026
Same author

Foreign Language Learning in Older Adults Modifies Resting-State Functional Connectivity Between the Subcortical Structures and the Cortex.

Aging medicine (Milton (N.S.W))·2026
Same author

Impaired event-related theta spectral coherence in emotional facial expression processing in neurodegenerative disorders.

Frontiers in human neuroscience·2026

Simple short-term memory tasks are effective for neuroimaging studies in young adults. These tasks show high accuracy and increased brain activity in key cognitive areas, supporting their use in aging research.

Area of Science:

  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Neuroimaging studies on aging cognition need tasks with high accuracy and significant cortical modulation.
  • Simple delayed-response tasks are proposed as suitable for these requirements.

Purpose of the Study:

  • To test if simple delayed-response tasks meet the criteria for neuroimaging studies in young adults.
  • To evaluate the performance and cortical activity during short-term memory (STM) and no-STM tasks.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was used in healthy young adults.
  • A short-term memory (STM) task involving a 5-second delay and a no-short-term-memory (NSTM) control task were employed.
  • Performance accuracy and cortical activation patterns were analyzed.

Related Experiment Videos

Main Results:

  • Both STM and NSTM tasks demonstrated high performance accuracy (approximately 95%).
  • The STM task significantly enhanced cortical responses in bilateral dorsolateral prefrontal cortex (Brodmann area 8-9), premotor cortex (BA 6L, BA 6M), and parietal areas (BA 40, BA 7) compared to the NSTM task.
  • Stronger cortical activation was observed in the right hemisphere (BA 8-9, BA 6L) during the STM task.

Conclusions:

  • A simple, one-bit short-term memory delayed-response task is accurately performed by young adults.
  • This task effectively modulates bilateral fronto-parietal cortical activity.
  • The findings suggest this task is suitable for future cognitive neuroimaging research on aging.