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Updated: Aug 18, 2026
Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery (SALLI) MRI in Rats
Published on: July 19, 2013
Determination of water compartments in rat myocardium using combined D-T1 and T1-T2 experiments
John Georg Seland1, Morten Bruvold, Henrik Anthonsen
1Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, N-7489 Trondheim, Norway. john.seland@medisin.ntnu.no
Abstract:
We have used combined D-T1 and T1-T2 correlation experiments to explore water compartments in rat heart tissue (myocardium). The results show that two main compartments can be identified, which we assign to extracellular (ec) and intracellular (ic) water. The exchange rate of water across the cell membrane was found to be on the order of 0.1 Hz. In addition, the T1-T2 correlation measurements indicate that the ic compartment contain two T2 populations.
