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Published on: August 2, 2024
Laryngotracheal consequences of pediatric cardiac surgery
Samir S Khariwala1, Walter T Lee, Peter J Koltai
1Cleveland Clinic Foundation, Head and Neck Institute, Cleveland, OH, USA.
Insights
Pediatric patients with congenital heart disease frequently develop laryngeal anomalies like subglottic stenosis and vocal cord paralysis, often due to intubation and ventilation. Early recognition and intervention are key for managing these airway complications.
Area of Science:
- Otolaryngology
- Pediatric Cardiology
- Pediatric Critical Care
Background:
- Congenital cardiac defects often necessitate interventions leading to potential airway complications.
- Pediatric patients undergoing cardiac surgery are at risk for laryngotracheal anomalies.
Purpose of the Study:
- To determine the incidence and characteristics of clinically significant laryngotracheal anomalies in pediatric patients undergoing surgical repair of congenital cardiac defects.
- To identify common anomalies and their association with cardiac diagnoses and interventions.
Main Methods:
- Single-center retrospective review of pediatric patients requiring surgical treatment for congenital heart disease over a 4-year period.
- Analysis of 48 patients who received otolaryngology consultations, examining cardiac diagnosis, consultation reason, examination findings, and follow-up.
Main Results:
- Subglottic stenosis occurred in 33% of patients (16/48), with 3 requiring tracheotomy and 4 needing reconstruction.
- Vocal cord paralysis was diagnosed in 19% (9/48) for unilateral and 6% (3/48) for bilateral cases.
- Left-sided vocal cord paralysis was associated with aortic arch repair in most patients.
Conclusions:
- Pediatric patients with congenital heart disease are prone to laryngeal anomalies from intubation, ventilation, and nerve injury.
- Subglottic stenosis is the most common abnormality, manageable with early endoscopic debridement or more invasive interventions for established cases.
- Unilateral vocal cord paralysis often resolves, while bilateral paralysis presents a persistent management challenge.
Objective:
To determine the incidence and character of clinically significant laryngotracheal anomalies in pediatric patients undergoing surgical repair of congenital cardiac defects at a tertiary care center.
Design:
Single-center retrospective review.
Patients:
The charts of pediatric patients who required surgical treatment for congenital heart disease over a 4-year period were reviewed. Forty-eight of 1957 patients were seen in inpatient consultation by the otolaryngology service. The parameters studied included cardiac diagnosis, reason for consultation, findings on examination, and follow-up.
Results:
There were 16 (33%) cases of subglottic stenosis, which were graded according to the Cotton-Myer classification system as follows: grade 1 (n=8); grade 2 (n=3); and grade 3 (n=5). Three of the 16 patients with subglottic stenosis required tracheotomy and 4 required laryngotracheal reconstruction. Nine (19%) of the 48 patients were diagnosed as having unilateral true vocal cord paralysis and 3 (6%) as having bilateral paralysis. With the exception of 1 patient, all patients with true vocal cord paralysis on the left side had undergone repair of the aortic arch.
Conclusions:
Pediatric patients with congenital cardiac disease are predisposed to laryngeal anomalies owing to (1) frequent intubation, (2) prolonged ventilatory support, and (3) recurrent laryngeal nerve injury. In our patients, subglottic stenosis was the most common laryngeal abnormality. When recognized early, in the eschar phase, most of these cases can be managed with sequential endoscopic debridement, which is conceptually similar to debridement that is performed after functional endoscopic sinus surgery. Established stenosis requires more vigorous intervention, the invasive degree of which depends on the length and circumference of the narrowing. Unilateral vocal paralysis tends to be a self-limited problem, while an elegant solution to bilateral paralysis remains elusive.
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