A molecular model to explain paclitaxel and docetaxel sensitivity changes through adduct formation with primary

Sunil S Iyer1, Songmei Gao, Zong-Ping Zhang

  • 1Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, 23298-0533, USA.

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Mass Spectrometry of Amines

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Mass Spectrometry: Amine Fragmentation00:55

Mass Spectrometry: Amine Fragmentation

Amines can be identified using mass spectroscopy based on their characteristic fragmentation patterns. The molecular ions of amines undergo fragmentation via ⍺-cleavage. The ⍺-cleavage of the carbon-carbon bonds in amines generates an alkyl radical and resonance-stabilized nitrogen-containing cation.
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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
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Mass Spectrometry: Carboxylic Acid, Ester, and Amide Fragmentation

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SDS-PAGE01:27

SDS-PAGE

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