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Intestinal transplantation: the evaluation process.

Jill I Robinson1, Rachel W Spencer

  • 1Georgetown University Hospital, Washington, DC, USA.

Progress in Transplantation (Aliso Viejo, Calif.)
|April 21, 2005
PubMed
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Intestinal transplantation is now an acceptable therapy for intestinal failure, thanks to advances in surgery and immunosuppression. Early evaluation and selection are crucial for successful outcomes in this complex procedure.

Area of Science:

  • Gastroenterology and Hepatology
  • Transplant Surgery
  • Organ Transplantation

Background:

  • Intestinal transplantation has evolved significantly over four decades.
  • Recent medical position statements recognize it as a viable therapy for intestinal failure.
  • Key advancements include surgical techniques, immunosuppression, and management of rejection and infection.

Purpose of the Study:

  • To define and analyze the critical evaluation process for intestinal transplantation.
  • To highlight the importance of early referral and candidate selection.
  • To discuss United Network for Organ Sharing (UNOS) listing criteria.

Main Methods:

  • Review of current medical literature and position statements.
  • Analysis of the components of the pre-transplant evaluation period.

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  • Discussion of organ sharing and listing criteria.

    • Main Results:

    • The evaluation process is fundamental to successful intestinal transplantation.
    • Early identification and selection of appropriate candidates are paramount.
    • UNOS listing criteria guide the selection process.

    Conclusions:

    • Intestinal transplantation is an established therapy for intestinal failure.
    • A rigorous and timely evaluation process is essential for patient success.
    • Understanding UNOS criteria is vital for listing candidates.