Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Response entropy increases during painful stimulation.

Peggy Wheeler1, William E Hoffman, Verna L Baughman

  • 1Anesthesiology Department, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

Journal of Neurosurgical Anesthesiology
|April 21, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atypical Presentation of a Ruptured Anterior Communicating Artery Aneurysm With Subdural, Intraparenchymal, and Subarachnoid Hemorrhage.

Cureus·2024
Same author

The Effect of a Required 48-Hour Window to Schedule Genetic Counseling on Time From Diagnosis of Breast Cancer to Surgery.

Clinical journal of oncology nursing·2024
Same author

Patient satisfaction following mastectomy: Comparing the standard postoperative bra and a novel medical recovery bra.

Nursing management·2023
Same author

Outcome Measurement: Patient Satisfaction Scores and Contact With Oncology Nurse Navigators.

Clinical journal of oncology nursing·2019
Same author

Correction to Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor.

Journal of medicinal chemistry·2018
Same author

Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate.

Journal of medicinal chemistry·2018

Response entropy (RE) can indicate frontal electromyography (FEMG) during painful stimuli, suggesting patient arousal. This method may help identify inadequate anesthesia, even during paralysis.

Area of Science:

  • Anesthesiology
  • Neurophysiology

Background:

  • Frontal electromyography (FEMG) may increase during painful stimulation, indicating patient arousal.
  • The Datex-Ohmeda Entropy Module measures state entropy (SE) from EEG and response entropy (RE) from EEG and FEMG.

Purpose of the Study:

  • To determine if the RE-SE difference, indicating FEMG, increases during painful stimuli.
  • To investigate if this increase is related to paralysis or anesthesia depth.

Main Methods:

  • Measured SE and RE in unanesthetized patients.
  • Administered 0.8% or 1.4% isoflurane anesthesia with paralysis.
  • Assessed RE-SE difference during painful stimuli (catheter/pin placement, tetanic stimulation).

Main Results:

Related Experiment Videos

  • Painful stimuli increased RE-SE difference above baseline in some patients, regardless of paralysis.
  • Increased RE-SE was associated with increased SE, blood pressure, and heart rate.
  • Increased RE-SE was observed more frequently with 0.8% isoflurane compared to 1.4%.

    • Conclusions:

    • Increased RE during painful stimuli reflects FEMG and is not dependent on paralysis recovery.
    • The RE-SE difference may be a useful indicator of inadequate anesthesia and patient arousal.
    • Lower isoflurane concentrations may be associated with a higher likelihood of detecting arousal via RE-SE.