Related Experiment Video
Updated: Aug 10, 2026
Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt
Published on: May 7, 2015
Transjugular intrahepatic cavoportal shunt for Budd-Chiari syndrome
1Department of Radiology, The Aga Khan University Hospital, Karachi, Pakistan.
Insights
Budd-Chiari syndrome (BCS) treatment can be challenging. This case demonstrates successful transcaval TIPS in a young woman with protein S and C deficiency, resolving severe ascites.
Area of Science:
- Hepatology
- Interventional Radiology
- Vascular Surgery
Background:
- Budd-Chiari syndrome (BCS) involves hepatic venous outflow obstruction, with limited therapeutic options.
- Protein S and C deficiency are prothrombotic conditions that can contribute to BCS.
- Severe ascites is a common and debilitating symptom of BCS.
Observation:
- A 21-year-old woman presented with Budd-Chiari syndrome and gross ascites due to protein S and C deficiency.
- Initial transjugular intrahepatic portosystemic shunt (TIPS) placement was unsuccessful due to occluded hepatic veins.
Findings:
- Transcaval TIPS was successfully performed in this BCS patient.
- The procedure had no serious complications.
- Successful shunt creation led to resolution of the patient's ascites.
Implications:
- Transcaval TIPS is a viable alternative for BCS patients with inaccessible hepatic veins.
- This approach offers a potential solution for complex BCS cases.
- Effective management of BCS can significantly improve patient outcomes and quality of life.
Abstract:
Budd-Chiari syndrome (BCS) is characterized by obstruction of the hepatic venous outflow tract. Therapeutic options for BCS are limited. We report a case of a 21-year-old woman with protein S and C deficiency with gross ascites. Treatment with transjugular intrahepatic portosystemic shunt (TIPS) was attempted, which revealed occluded hepatic veins, so transcaval TIPS was performed. No serious procedure-related complication occurred. After successful shunt creation, the patient's symptoms subsided and she was discharged and followed up for 6 months.
