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Psychological interventions for non-ulcer dyspepsia
The Cochrane Database of Systematic Reviews
|April 23, 2005
Summary
Psychological interventions may help non-ulcer dyspepsia (NUD) symptoms, but evidence is limited. More research is needed to confirm the effectiveness of these treatments for NUD patients.
Area of Science:
- Gastroenterology
- Psychiatry
- Evidence-based medicine
Background:
- Non-ulcer dyspepsia (NUD) patients exhibit higher psychological distress, including anxiety and depression.
- The efficacy of psychological interventions for NUD remains uncertain.
Purpose of the Study:
- To evaluate the effectiveness of various psychological interventions for NUD.
- Assess improvements in dyspepsia symptom and quality of life scores.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) and quasi-randomized studies.
- Searched multiple databases (Cochrane, MEDLINE, EMBASE, PsycLIT, CINAHL) and contacted experts.
- Included interventions: psychotherapy, psychodrama, CBT, relaxation therapy, hypnosis.
Main Results:
- Only four trials were identified, with diverse interventions and insufficient data for meta-analysis.
- All trials indicated potential benefits for dyspepsia symptoms lasting one year.
- Methodological concerns included small sample sizes and unadjusted statistical analyses; unadjusted data was not significant.
- Low recruitment and high dropout rates were noted, particularly in group therapy.
Conclusions:
- Insufficient evidence exists to confirm the efficacy of psychological interventions for non-ulcer dyspepsia.
- Further high-quality RCTs are required to establish the role of psychological therapies in NUD management.