Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tubal flushing for subfertility.

N Johnson1, P Vandekerckhove, A Watson

  • 1Department of Obstetrics & Gynaecology, University of Auckland, PO Box 92019, Auckland, New Zealand, 1003. n.johnson@auckland.ac.nz

The Cochrane Database of Systematic Reviews
|April 23, 2005
PubMed
Summary

Tubal flushing with oil-soluble contrast media significantly increases pregnancy and live birth rates compared to no intervention. Further research is needed to compare oil-soluble with water-soluble media for optimal fertility outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A lateral hypothalamic region supporting diverse visual processing and modulation of visually-guided behaviour.

Nature communications·2025
Same author

Author Correction: ROBIN: Reference observatory of basins for international hydrological climate change detection.

Scientific data·2025
Same author

Single Nucleotide Polymorphisms and Their Association with Coronary Artery Aneurysms and IVIG Resistance in Kawasaki Disease in Ireland.

Pediatric cardiology·2025
Same author

ROBIN: Reference observatory of basins for international hydrological climate change detection.

Scientific data·2025
Same author

Interrelationships between social exclusion, mental health and wellbeing in adolescents: insights from a national <i>Youth Survey</i>.

Epidemiology and psychiatric sciences·2025
Same author

The LTAR Grazing Land Common Experiment at Platte River High Plains Aquifer.

Journal of environmental quality·2024

Area of Science:

  • Reproductive Medicine
  • Infertility Treatment
  • Diagnostic Imaging

Background:

  • The potential fertility-enhancing effect of diagnostic tubal patency testing has been debated for decades.
  • The comparative efficacy of oil-soluble versus water-soluble contrast media for fertility enhancement remains unclear.
  • Current routine practice for fertility delay does not typically include tubal flushing.

Purpose of the Study:

  • To evaluate the impact of tubal flushing with oil- or water-soluble contrast media on subsequent fertility outcomes in infertile couples.

Main Methods:

  • A systematic review of randomized controlled trials was conducted, searching multiple databases up to March 2004.
  • Included trials compared tubal flushing with oil-soluble media, water-soluble media, or no treatment.

Related Experiment Videos

  • Primary outcome was live birth; secondary outcomes included pregnancy, miscarriage, ectopic pregnancy, and complications.

    • Main Results:

    • Tubal flushing with oil-soluble media significantly increased the odds of live birth and pregnancy compared to no intervention.
    • No randomized controlled trials (RCTs) assessed water-soluble media versus no intervention.
    • While oil-soluble media showed a potential live birth benefit over water-soluble media, this finding requires cautious interpretation due to heterogeneity and conflicting trial quality.

    Conclusions:

    • Evidence supports the effectiveness of oil-soluble contrast media for tubal flushing in improving pregnancy and live birth rates compared to no intervention.
    • Further high-quality RCTs are necessary to compare oil-soluble and water-soluble media, and water-soluble media against no intervention.
    • Additional research is warranted to elucidate the mechanism behind the fertility-enhancing effects of oil-soluble media.