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Related Experiment Videos

Antibiotic use for irreversible pulpitis.

J V Keenan1, A G Farman, Z Fedorowicz

  • 1U.S. Naval Health Clinics United Kingdom, PSC 821, Box 51, FPO AE 09421-0051, UK. keenanjv@yahoo.com

The Cochrane Database of Systematic Reviews
|April 23, 2005
PubMed
Summary
This summary is machine-generated.

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Systemic antibiotics do not significantly improve pain relief for irreversible pulpitis when compared to placebo. This finding suggests that antibiotics are not an effective treatment for managing pain in irreversible pulpitis.

Area of Science:

  • Dentistry
  • Pharmacology

Background:

  • Irreversible pulpitis causes severe pain and is a common reason for emergency dental visits.
  • Standard treatment involves pulp removal, but some dentists prescribe antibiotics for pain relief.

Purpose of the Study:

  • To evaluate the effectiveness of systemic antibiotics in relieving pain associated with irreversible pulpitis.

Main Methods:

  • A systematic review including one randomized controlled trial.
  • Searched multiple databases (Cochrane, MEDLINE, EMBASE) up to September 2004.
  • Compared pain relief in patients receiving antibiotics plus analgesics versus placebo plus analgesics.

Main Results:

  • One trial with 40 participants showed no significant difference in pain ratings between antibiotic and placebo groups.

Related Experiment Videos

  • No significant difference in the amount of analgesic medication (ibuprofen, Tylenol) used.
  • Penicillin did not significantly reduce analgesic use compared to placebo (P > 0.05).

    • Conclusions:

    • Evidence from one small, low-powered trial suggests no significant difference in pain relief.
    • Antibiotics may not be effective for managing pain in irreversible pulpitis when added to analgesics.