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Updated: Aug 18, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
Published on: March 12, 2013
[Cardiac involvement in Kearns-Sayre syndrome]
Carlos F Barrera-Ramírez1, Héctor M Barragán-Campos, Hermes Ilarraza
1Departamento de Cardiología Intervencionista, Centro Hospitalario La Concepción, Saltillo, México. carlosfbarrera@yahoo.com
Abstract:
The mitochondrial cytopathies or oxidative-phosphorylation diseases are a diverse group of disorders that result from the structural, biochemical, or genetic derangement of mitochondria. Because mitochondrial dysfunction can affect the most highly energy-dependent organs, cardiac involvement is frequent in these diseases. To identify the clinical features of Kearns-Sayre syndrome, an entity associated with this group of diseases, we evaluated cardiac structure and function in 5 patients with Kearns-Sayre syndrome and followed the clinical course of these patients for 5 years.
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