Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Clear cell renal cell carcinoma.

David J Grignon¹, Mingxin Che

¹Department of Pathology, Wayne State University, Harper University Hospital, Detroit, MI, USA. dgrignon@med.wayne.edu

Clinics in Laboratory Medicine

|April 26, 2005

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Urothelial carcinoma in situ with "early papillary formation" vs "lateral spread/shoulder lesion" of prior high-grade noninvasive papillary urothelial carcinoma: A survey of pathologist and urologist interpretations.

American journal of clinical pathology·2024

Same author

Recurrent KRAS mutations are early events in the development of papillary renal neoplasm with reverse polarity.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2022

Same author

EWSR1-PATZ1 fusion renal cell carcinoma: a recurrent gene fusion characterizing thyroid-like follicular renal cell carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2021

Same author

Distal Tubular Hyperplasia: A Proposal for a Unique Form of Renal Tubular Proliferation Distinct From Papillary Adenoma.

The American journal of surgical pathology·2021

Same author

[Molecular pathology of urogenital tumors : Recommendations from the 2019 International Society of Urological Pathology (ISUP) Consensus Conference].

Der Pathologe·2021

Same author

Morphologic and Immunohistochemical Characteristics of Fluorescent In Situ Hybridization Confirmed TFE3-Gene Fusion Associated Renal Cell Carcinoma: A Single Institutional Cohort.

The American journal of surgical pathology·2020

Clear cell renal cell carcinoma (RCC) is the most common adult kidney cancer with a poor prognosis. A distinct subtype with multi-locular cystic architecture shows unique clinicopathologic features.

Area of Science:

Oncology
Nephrology
Pathology

Background:

Clear cell renal cell carcinoma (RCC) is the predominant subtype of kidney cancer in adults.
It presents the most unfavorable prognosis among common epithelial kidney tumors.
Histopathological examination reveals diverse morphologic patterns.

Purpose of the Study:

To highlight the clinicopathologic features of a distinct subtype of clear cell RCC.
To emphasize the significance of multi-locular cystic architecture in kidney cancer classification.

Main Methods:

Histopathological analysis of clear cell RCC cases.
Correlation of morphological patterns with clinical data.

Main Results:

Related Experiment Videos

Clear cell RCC exhibits a spectrum of histological variations.

Cases with multi-locular cystic architecture represent a distinct clinicopathologic subtype.

Conclusions:

The multi-locular cystic architecture is a key feature differentiating a specific subtype of clear cell RCC.
Recognition of this subtype is crucial for understanding its unique clinicopathologic behavior.