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[Mumps meningitis: a case mix in a Neurology Department]

P E Jiménez-Caballero1, M Serviá, B Mondejar-Marín

  • 1Servicio de Neurología, Hospital Virgen de la Salud, Toledo, Spain. pjimenez1010j@yahoo.es

Revista De Neurologia
|April 26, 2005
PubMed
Abstract

Insights

Meningitis linked to parotiditis virus infection is rare but serious, primarily affecting young males. Prompt diagnosis and awareness are crucial, especially in underdeveloped regions, as vaccination has significantly reduced cases.

Area of Science:

  • Virology
  • Neurology
  • Infectious Diseases

Background:

  • Parotiditis is a viral infection causing inflammation of salivary glands, potentially affecting other organs like testicles, meninges, and pancreas.
  • Clinical meningitis occurs in 1-10% of parotiditis cases, typically 4-10 days post-infection.

Purpose of the Study:

  • To analyze the clinical and analytical characteristics of patients with parotiditis-associated meningitis.
  • To understand the presentation and outcomes of this rare complication.

Main Methods:

  • Retrospective analysis of hospital discharge reports over 12 years.
  • Inclusion criteria: acute meningeal syndrome with positive IgM titres for the parotiditis virus.
  • 13 eligible cases identified.

Main Results:

  • Mean age of patients was 16.5 years; 92.3% were male.
  • Parotiditis preceded meningitis by an average of 8.3 days.
  • Cerebrospinal fluid analysis revealed a lymphocyte profile with normal glucose levels; no sequelae observed.

Conclusions:

  • Vaccination campaigns have significantly decreased parotiditis-related meningitis cases since the late 1990s.
  • The parotiditis virus should be considered in meningitis cases among young males, particularly from underdeveloped countries.

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