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Correlation of perforating vein incompetence with extent of great saphenous insufficiency: cross sectional study
Anton Krnić1, Niksa Vucić, Zvonimir Sucić
1Department of Radiology, Holy Ghost General Hospital, Sveti Duh 64, 10000 Zagreb, Croatia., anton.krnic@zg.t-com.hr
Insights
The number and diameter of incompetent perforators correlate with great saphenous vein insufficiency. Clinical presentation worsens with deteriorating perforator incompetence, but association with deep venous reflux is weak.
Area of Science:
- Vascular Surgery
- Phlebology
- Ultrasound Diagnostics
Background:
- Great saphenous vein (GSV) insufficiency is a common cause of chronic venous disease.
- Perforating veins connect superficial and deep venous systems; their incompetence can contribute to venous hypertension.
Purpose of the Study:
- To investigate the relationship between perforating vein incompetence and the severity of great saphenous vein insufficiency.
- To assess the correlation between perforator characteristics and clinical presentation (CEAP classification).
Main Methods:
- Duplex ultrasound was employed in 118 lower limbs to assess perforating vein number and diameter, GSV reflux, and deep reflux.
- Patients were categorized by clinical severity using the CEAP classification (grades 0-4).
Main Results:
- A significant positive correlation was found between the number/diameter of incompetent perforators and the extent of GSV insufficiency (r=0.55, r=0.44; P<0.001).
- Both perforator number and diameter increased significantly with worsening CEAP grades (P<0.001).
- Perforator diameter was significantly larger in limbs with deep reflux (P=0.023), though the number of incompetent perforators did not differ significantly.
Conclusions:
- Increased number and diameter of perforators are associated with greater GSV insufficiency.
- Clinical severity correlates with duplex ultrasound findings of perforator incompetence.
- The association between perforator incompetence and deep venous reflux appears less significant.
Aim:
To explore the correlation between perforating vein incompetence and the extent of great saphenous vein insufficiency according to Hach.
Methods:
Duplex ultrasound was used to determine the number of incompetent perforators and diameter of perforating veins, and the level of great saphenous vein reflux and the presence or absence of deep reflux in 118 lower limbs (59 patients). There were 19 limbs with no clinical evidence of venous disease (CEAP - clinical, etiological, anatomical, pathological grade 0), 16 limbs with telangiectasias only (CEAP grade 1), 36 limbs with varicose veins (CEAP 2), 26 limbs with edema (CEAP 3), and 21 limb affected with lipodermatosclerosis but not ulcer (CEAP 4).
Results:
Both the number of incompetent perforators and the average diameter of duplex detectable perforators per limb correlated significantly with the extent of great saphenous vein insufficiency (Pearson correlation coefficients were 0.55 and 0.44, respectively; P<0.001 for both). The number of incompetent perforators and the average diameter of perforators per limb were significantly higher with the deteriorating CEAP grade (Kruskal-Wallis H test; P<0.001). The mean number of incompetent perforators per limb did not differ significantly in the absence or presence of deep reflux (0.8-/+1.26 vs 1.3-/+1.6, t test, P=0.172), the average diameter of perforators per limb was higher in the presence of deep reflux (2.4-/+2 mm vs 3.7-/+1.1 mm, t test, P=0.023).
Conclusion:
The extent of great saphenous vein insufficiency correlated with an increase in the number and the diameter of perforators. The perforators' association with deep venous reflux was much poorer. Clinical presentation worsened with the deteriorating duplex signs of perforators' incompetence.
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