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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Candidal arthritis after complete treatment of systemic candidiasis

Wen-Bin Hsieh1, Cheung Leung

  • 1Division of Neonatology, Department of Pediatrics, Far Eastern Memorial Hospital, Panchiao, Taipei, Taiwan, ROC.

Journal of the Chinese Medical Association : JCMA
|April 27, 2005
PubMed

Insights

Systemic candidemia in premature infants can lead to complications like arthritis. Long-term follow-up and appropriate antifungal treatment, such as fluconazole for arthritis, are crucial for successful outcomes.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Mycology

Background:

  • Invasive candidal infections (ICIs) pose a significant threat in neonatal intensive care units (NICUs).
  • Complications of ICIs include arthritis, endocarditis, meningitis, and endophthalmitis.
  • Rising incidence of ICIs necessitates review of management strategies.

Observation:

  • A case of a premature infant with systemic candidemia is presented.
  • Arthritis was diagnosed 6 months post-amphotericin B therapy.
  • The infant received successful treatment for candidal arthritis with oral fluconazole.

Findings:

  • Systemic candidemia can have delayed complications, such as arthritis.
  • Oral fluconazole is an effective treatment for candidal arthritis in neonates.
  • Prolonged follow-up is essential for infants treated for candidemia.

Implications:

  • Early and comprehensive management of neonatal candidemia is vital.
  • Consideration of extended antifungal therapy may be necessary to prevent complications.
  • This case highlights the importance of vigilant monitoring for late-onset complications in high-risk infants.

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