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Characterization of alphaX I-domain binding to Thy-1

Jeongsuk Choi1, Lisette Leyton, Sang-Uk Nham

  • 1Divisions of Science Education and Biology, Kangwon National University, Choonchun, Kangwon, Republic of Korea.

Biochemical and Biophysical Research Communications
|April 27, 2005
PubMed
Summary

The alphaX-beta2 integrin specifically binds to Thy-1, a protein involved in cell signaling. This interaction, dependent on divalent cations, suggests a potential role for alphaX-beta2 in regulating T cell functions.

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