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Target identification for a promising anti-lupus drug
1Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chemistry & Biology
|April 27, 2005
Abstract:
Target identification is one of the more difficult aspects of modern chemical genetics. In this issue of Chemistry & Biology, Johnson et al. provide a compelling case for going through the trouble. As a byproduct of their identification of the cellular target of an anti-lupus compound, they have uncovered a powerful tool for the characterization of a fascinating molecular machine, the F1F0-ATP synthase.
