Related Experiment Video

Updated: Aug 18, 2026

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

Catheter ablation guided by termination of postinfarction ventricular tachycardia by pacing with nonglobal capture

Frank Bogun1, Subramaniam C Krishnan, Joseph E Marine

  • 1University of Michigan, Ann Arbor, 48109, USA. fbogun@umich.edu

Heart Rhythm
|April 27, 2005
PubMed

Insights

Pacing during ventricular tachycardia (VT) that terminates the arrhythmia with nonglobal capture helps identify critical circuit components for ablation. This method is valuable for targeting postinfarction VT, even without documented concealed entrainment.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Postinfarction ventricular tachycardia (VT) arises from reentrant circuits.
  • Identifying critical components of these circuits is key for successful ablation.

Purpose of the Study:

  • To investigate the prevalence and utility of termination of VT by pacing with nonglobal capture.
  • To determine if this criterion effectively identifies ablation targets in patients with postinfarction VT.

Main Methods:

  • Prospective study of 34 patients with postinfarction VT undergoing radiofrequency catheter ablation.
  • Left ventricular mapping with pacing during VT at abnormal electrogram sites.
  • Radiofrequency energy delivery if VT terminated with nonglobal capture.

Main Results:

  • Sixty-two VTs were mapped; 101 endocardial sites showed concealed entrainment.
  • VT terminated with nonglobal capture at 15 sites (5% of mapped sites).
  • Radiofrequency ablation at these 15 sites successfully terminated VT and prevented reinduction.

Conclusions:

  • Termination of VT by pacing with nonglobal capture occurs in about one-third of patients.
  • This finding is a specific criterion for identifying critical reentrant circuit components.
  • The criterion is valuable whether or not concealed entrainment is documented.
Abstract

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