Related Experiment Video
Updated: Aug 10, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Preexcitation masking underlying aberrant conduction: an atriofascicular accessory pathway functioning as an ectopic
Ernest W Lau1, Martin S Green, David H Birnie
1University of Ottawa Heart Institute, Ontario, Canada.
An unusual accessory pathway mimicked a right bundle branch, causing broad QRS complexes. This case highlights a split atrioventricular node-bundle branch system responsible for normal and preexcited tachycardias.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Anatomy
Background:
- Broad QRS complexes in electrocardiograms (ECGs) can result from preexcitation or aberrant conduction.
- Accessory pathways are a common cause of supraventricular tachycardias.
- Split atrioventricular node-bundle branch (AVN-BB) systems are rare congenital anomalies.
Observation:
- This study presents an unusual case of an atriofascicular accessory pathway.
- The pathway functioned as an ectopic right bundle branch.
- This created a split AVN-BB system.
Findings:
- The accessory pathway facilitated physiologically normal ventricular activation.
- It also participated in pathologic preexcited tachycardias.
- This demonstrates a unique mechanism for both normal conduction and arrhythmia generation.
Implications:
- Understanding such anomalies is crucial for accurate ECG interpretation.
- This case expands knowledge of accessory pathway function and AVN-BB system variations.
- It may inform novel therapeutic strategies for related arrhythmias.
Related Concept Videos
Mechanism of Cardiac Arrhythmias
Conduction System of the Heart
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Conduction System of the Heart
This system relies on the unique properties of nodal and Purkinje cells:...
Dysrhythmias IV: Characteristics of Bradyarrhythmias
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

