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Correction of HIV-associated thrombocytopenia with low doses of interferon alfa
K P Murphy1, M D Stein, R P D'Amico
1Brown University Program in Medicine, Rhode Island Hospital, Providence 02903.
Southern Medical Journal
|May 1, 1992
Abstract:
We have presented a case of HIV-associated thrombocytopenia successfully treated with low dose interferon alfa-2a. Increases in platelet levels were achieved within 1 week without hospitalization or surgery. Further, the patient had no systemic side effects from therapy. Zidovudine alone was ineffective in maintaining noncritical platelet counts. Interferon alfa-2a is a nonimmunosuppressive, nonsurgical therapy that can correct HIV-associated thrombocytopenia without requiring hospitalization.