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Updated: Aug 18, 2026

Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy
Published on: February 20, 2018
[Relationship between respiration exchange ratio and muscle oxygen content measured by near-infrared spectroscopy]
Guo-dong Xu1, Ming Liu, Gang Chen
1Sports Kinetics Department of Wuhan Institute of Physical Education, Wuhan Hubei, China. xguodong@email.wipe.edu.cn
Objective:
To study the relationship between respiration exchange ratio (RER) and tissue oxygen content in human skeletal muscle.
Method:
Using a portable tissue oximeter based on near-infrared spectroscopy (NIRS), the relative changes of skeletal muscle oxygen content were measured non-invasively and in vivo when healthy volunteers were performing an incremental intensity running protocol. The results were compared with heart rate (HR), VO2, VCO2, and RER.
Result:
In the experiment, the change in skeletal muscle oxygenation content of the volunteers was regular and has a significant close relationship to HR, VO2 and RER (P=0.01).
Conclusion:
It shows that NIRS is a new photonic technology which provides a measurable biomedical parameter for the evaluation of athlete's physique and training effect. It offers reference for monitoring and assessing training effect in vivo, real-time and non-invasively.
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