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Ziprasidone: a novel psychotropic with unique properties
Christos Ballas1, Calvin Yang, John O'Reardon
1PEEC, Ground Floor, Ravdin Building, 3400 Spruce St., Philadelphia, PA 19104, USA. christosballas@yahoo.com
Abstract:
Ziprasidone (Geodon) is a relatively new atypical antipsychotic medication with a unique pharmacological profile. It is indicated for the treatment of schizophrenia, but has also often been used off-label for other uses. This review summarizes its important properties, specifically the pharmacodynamic parameters, receptor-binding profile and relevance to clinical outcomes, side effects, and potential for drug-drug interactions and established clinical indications. Novel therapeutic applications and relevant clinical trials or reports are also examined. The authors review the current market and speculate on likely changes in 5 years.
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