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Neuroimaging in glioma therapy
John W Henson1, R Gilberto Gonzalez
1Division of Neuroradiology and Brain Tumor Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. henson@helix.mgh.harvard.edu
Expert Review of Neurotherapeutics
|April 28, 2005
Summary
Neuroimaging, including computed tomographic and magnetic resonance imaging, is crucial for brain tumor care. This review explores challenges in using these imaging techniques to measure brain tumor response and progression during therapy.
Area of Science:
- Neuroimaging
- Oncology
- Radiology
Background:
- Computed tomographic (CT) and magnetic resonance imaging (MRI) represent significant advancements in brain tumor patient care.
- Diffuse astrocytomas exhibit a strong correlation between imaging features, pathology, and clinical behavior.
- Current understanding of imaging's role in assessing brain tumor response and progression remains limited.
Purpose of the Study:
- To review unsolved problems in neuroimaging for measuring brain tumor response to therapy.
- To highlight the importance of advanced imaging techniques in oncology.
Main Methods:
- Literature review focusing on neuroimaging in brain tumor therapy response assessment.
- Analysis of current challenges and limitations in interpreting imaging data for treatment efficacy.
Main Results:
- Significant progress has been made in applying CT and MRI to brain tumor management.
- There is a need for further research into standardized imaging criteria for response evaluation.
- Understanding the correlation between imaging findings and treatment outcomes is an ongoing challenge.
Conclusions:
- Neuroimaging plays a vital role in the management of brain tumors.
- Further investigation is required to refine the use of imaging biomarkers for assessing treatment response and disease progression.
- Addressing current limitations will enhance the utility of neuroimaging in clinical practice.
