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Microbiological analysis of chronic dacryocystitis
Xuguang Sun1, Qingfeng Liang, Shiyun Luo
1Department of Eye Microbiology, Beijing Institute of Ophthalmology, China. sunxuguang@yahoo.com
Summary
Microbiology of chronic dacryocystitis revealed Staphylococcus and Corynebacterium as common bacteria. Levo-ofloxacin and amikacin showed the best effectiveness against these pathogens in vitro.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Chronic dacryocystitis is an infection of the lacrimal sac.
- Understanding the causative microorganisms is crucial for effective treatment.
Purpose of the Study:
- To investigate the microbiology of specimens from patients with chronic dacryocystitis.
- To identify predominant pathogens and their antibiotic sensitivities.
Main Methods:
- 100 samples from 91 patients with chronic dacryocystitis were cultured for aerobic and anaerobic bacteria and fungi.
- Isolates were identified using routine microbiological techniques.
- Antibiotic sensitivity testing was performed.
Main Results:
- 180 strains were isolated, with Staphylococcus species (34.5%) and Corynebacterium diphtheroides (15.5%) being most frequent.
- Fungi were present in 8% of samples, and actinomyces in 3%.
- Levo-ofloxacin and amikacin demonstrated the highest effectiveness in sensitivity tests.
Conclusions:
- Gram-positive cocci, particularly Staphylococcus species, are the predominant pathogens in chronic dacryocystitis.
- Levo-ofloxacin and amikacin are effective antibiotics against these pathogens in vitro.