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Related Experiment Videos

[Onychomycoses caused by moulds].

G Achten, J Wanet-Rouard, L Wiame

    Dermatologica
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Saprophytic fungi invade nail keratin through the hyponychium and nail plate, causing various onychomycosis clinical pictures. Understanding these invasion pathways is crucial for diagnosing fungal nail infections.

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    Area of Science:

    • Mycology
    • Dermatology
    • Pathology

    Context:

    • Investigates the mechanisms of fungal nail invasion.
    • Examines both in vitro and in vivo models of saprophyte interaction with nail keratin.

    Purpose:

    • To elucidate the pathways by which saprophytic fungi invade nail keratin.
    • To correlate specific invasion routes with clinical presentations of onychomycosis.

    Summary:

    • Saprophytes invade nail keratin via hyponychium and nail plate penetration by mycelial filaments and spores.
    • Electron microscopy reveals intercellular and intracellular invasion by mycelial filaments.
    • Specific invasion patterns, including 'boring hyphae,' contribute to clinical conditions like onychomycosis, pachyonychia, and leuconychomycosis.

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    Impact:

    • Highlights the importance of diagnostic criteria for identifying saprophytic onychomycosis.
    • Provides insights into the pathogenesis of fungal nail diseases.
    • Informs clinical diagnosis and management strategies for onychomycosis.