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M-VAC versus CisCA--chemotherapy in the treatment of advanced bladder cancer
D Heimbach1, M Wirth, H Frohmüller
1Department of Urology, University of Würzburg Medical School, FRG.
Urologia Internationalis
|January 1, 1992
Abstract:
The results of this study do not demonstrate a superiority of M-VAC chemotherapy over a modified CisCA regimen chemotherapy. M-VAC, however, proved less toxic than CisCA in terms of side effects. Neither CisCA nor M-VAC was effective as a curative treatment for patients with distant metastases. A durable complete remission of 22.5 months was seen in only 2 of the 12 patients with locally advanced tumors without distant metastases treated with M-VAC, and one of 35 months was observed in only 1 of the 6 cases with locally advanced tumors treated with CisCA chemotherapy.