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Primary localized amyloidosis of the bladder: a case of AL (lambda) amyloid protein and combination therapy using
T Nishiyama1, F Gejyo, Y Katayama
1Department of Urology, Niigata University School of Medicine, Japan.
Urologia Internationalis
|January 1, 1992
Abstract:
We report a case of primary localized amyloidosis of the bladder with amyloid deposits which was characterized as being of immunoglobulin light chain origin (AL) including lambda type (A lambda) and P component (AP) using the KMnO4 pretreatment method and immunohistochemical procedures. The patient was treated successfully with intravesical dimethyl sulfoxide instillation and oral administration of high-dose cepharanthin after transurethral resection. Combination therapy with dimethyl sulfoxide and cepharanthin was shown to be useful for primary localized amyloidosis of the bladder.