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DSM criteria for major depression: evaluating symptom patterns using latent-trait item response models

Steven H Aggen1, Michael C Neale, Kenneth S Kendler

  • 1Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia and Virginia Commonwealth University, Richmond, VA 23298-0126, USA. saggen@hsc.vcu.edu

Psychological Medicine
|April 29, 2005
PubMed
Summary

Item response models offer a superior method for assessing major depression (MD) liability compared to traditional diagnostic criteria. These models provide more accurate predictions of outcomes and better heritability estimates by treating symptoms as risk indicators.

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