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Updated: Aug 18, 2026

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
Published on: July 30, 2014
Abstract:
A model of actin sliding is proposed, which is based on the occurrence of actin-myosin interactions and the generation in actin filaments of elastic deformations of torsion, compression, and tension. Previously in experiments in vitro, an unusually stable right-handed axial rotation of actin filaments sliding relative to myosin with a rotation pitch of 1 microm was observed. However, the reported value of the rotation pitch is significantly greater (14 times) than the pitch of actin right-handed double helix (72 nm), which supposedly determines the rotation pitch of actin. This result is explained in terms of the model by the presence of the reverse turn of actin at each elementary step.
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