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Corneal endothelial deposits associated with rifabutin use
Anamaria Baptista Coutinho1, Devinder Cheema, Patricia R Pereira
1Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil. anamariacoutinho@hotmail.com
Purpose:
The aim of this study was to report on the possible development of corneal endothelial deposits resulting from the use of rifabutin.
Methods:
Case series consisting of 3 patients treated with rifabutin were retrospectively studied. Two of the patients were infected with human immunodeficiency virus. A corneal and external disease specialist performed a complete ophthalmologic exam and obtained medical histories of the patients.
Results:
All cases developed corneal endothelial deposits after previous use of rifabutin. The deposits were bilateral, yellow-white colored, stellate, and mainly peripheral.
Conclusions:
In these 3 cases, the unique positive ocular finding was corneal endothelial deposits, which may be related to the use of rifabutin.
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