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Visually self-induced seizures sensitive to round objects.

Knut Brockmann1, Peter Huppke, Michael Karenfort

  • 1Department of Pediatrics and Neuropediatrics, Georg-August-University, Göttingen, Germany. kbrock@med.uni-goettingen.de

Epilepsia
|April 29, 2005
PubMed
Summary
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This study describes a unique case of self-induced pattern-sensitive seizures in a child, triggered by visual stimuli like round objects. Effective treatment involved a combination of antiepileptic drugs (AEDs).

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Neurophysiology

Background:

  • Self-induced seizures are rare neurological events.
  • Pattern sensitivity in epilepsy is typically associated with specific visual stimuli like stripes.

Observation:

  • An 18-month-old boy presented with focal tonic seizures triggered by gazing at round objects.
  • The child exhibited self-induction of seizures, which provided temporary relief.
  • Seizure frequency and severity increased over time, including secondarily generalized tonic-clonic seizures.

Findings:

  • Electroencephalography (EEG) showed multifocal sharp-and-slow-waves interictally.
  • Ictal EEG revealed no abnormalities during focal seizures but showed rapidly generalizing discharges during generalized seizures.

Related Experiment Videos

  • No photoparoxysmic response was observed, differentiating it from typical photosensitive epilepsy.
  • Developmental stagnation occurred over two years despite various treatments.
  • Combined pharmacotherapy with valproate, sulthiame, and clobazam achieved seizure control.

    • Implications:

    • Geometric patterns beyond stripes can trigger focal seizures with secondary generalization.
    • The findings suggest a potential role for the synchronization of cortical neurons in pattern recognition-related epileptogenesis.
    • This case expands the understanding of pattern-sensitive epilepsy and its management in children.