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[Prevalence of systemic inflammatory syndromes at a tertiary pediatric intensive care unit]

Paulo R A Carvalho1, Letícia Feldens, Elizabeth E Seitz

  • 1Universidade Federal do Rio Grande do Sul, Porto Alegre, RS. carvalho.conex@uol.com.br

Jornal De Pediatria
|April 29, 2005
PubMed

Insights

Systemic inflammatory response syndrome (SIRS) is common in pediatric intensive care units, particularly infectious types. These patients face longer hospital stays and higher mortality risks.

Area of Science:

  • Pediatric critical care medicine
  • Infectious diseases
  • Inflammation research

Context:

  • Systemic inflammatory syndromes are frequently encountered in pediatric intensive care units (PICUs).
  • Understanding their prevalence and impact is crucial for patient outcomes.
  • This study focuses on a tertiary-care university PICU setting.

Purpose:

  • To determine the prevalence of systemic inflammatory syndromes upon PICU admission.
  • To analyze the relationship between these syndromes and length of hospital stay.
  • To assess the association with risk of death and actual mortality rates.

Summary:

  • A prospective study of 447 admissions in a pediatric ICU found a 68% prevalence of systemic inflammatory response syndrome (SIRS).
  • Infectious SIRS (sepsis, severe sepsis, septic shock) constituted two-thirds of cases.
  • Infectious SIRS was linked to significantly higher mortality risk, longer ICU stays, and increased observed mortality compared to non-infectious SIRS.

Impact:

  • High prevalence of SIRS, especially infectious types, impacts PICU resource utilization.
  • Findings highlight the critical nature of early identification and management of infectious SIRS in critically ill children.
  • This research informs clinical practice and resource allocation in pediatric critical care.
Abstract

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