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Updated: Aug 18, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Behçet's disease]
Bertrand Wechsler1, Lê Thi Huong Du-Boutin, Zahir Amoura
1Service de médecine interne, groupe hospitalier La Pitié-La Salpêtrière, 75651 Paris Cedex 13. bertrand.wechsler@psl.aphp.fr
Abstract:
Behçet's disease is a vasculitis of unknown origine. Mucocutaneous manifestations are necessary for diagnosis. Ocular and neurological involvements can lead to severe impairment. Arterial involvement may be lethal. Treatment is only symptomatic using steroids, colchicine and antiaggregant therapy. Immunosuppressive drugs are generally given for severe manifestations resistant to conventional therapy. Alpha interferon and infliximab are interesting in case of failure or relapses despite treatment. As in all chronic diseases, education and good observance are needed to improve prognosis.
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