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Published on: November 27, 2014
Seasonality of invasive Candida infection in neonates
N E Edi-Osagie1, A J B Emmerson
1Regional Neonatal Medical Unit, St Mary's Hospital for Women and Children, Manchester, UK. ngozi.edi-osagie@cmmc.nhs.uk
Aim:
To evaluate season of birth as a risk factor for the development of invasive Candida in our population of preterm low-birthweight infants.
Methods:
Retrospective identification of Candida-positive blood or cerebrospinal fluid (CSF) cultures in infants < 32 wk over an 8-y period.
Results:
There were 1400 admissions of infants < 32 wk gestation, of whom 52 (3.7%) developed invasive Candida infection. Thirty-eight of 52 (73%) occurred during the months September to February.
Conclusions:
It may be appropriate to consider seasonal associations when targeting selective antifungal chemoprophylaxis.
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