Related Experiment Video
Updated: Aug 18, 2026

A Catheter-Related Candida albicans Infection Model in Mouse
Published on: March 22, 2024
The association of Candida infection with intrauterine contraceptive device
S Demirezen1, O O Dirlik, M S Beksaç
1Hacettepe University, Faculty of Science, Department of Biology, Beytepe, Ankara, Turkey. sayeste@hacettepe.edu.tr
Abstract:
In order to analyse the relationship between intrauterine contraceptive device (IUCD) usage and Candida infection, we planned to examine cytologically the cervico-vaginal smears of 600 patients stained with Papanicolou method. Among 56 IUCD users 8 women had Candida infection (14%) while 44 of 544 non-users (8%) were infected by this fungus. Our detailed analyses indicated that the prolonged usage of Cu-IUCD may predispose the cervico-vaginal flora for Candida especially for the infectious "hyphae" form although statistically the correlation between IUCD usage and candidiasis was not significant (p>0.05). These findings imply the importance of controlled IUCD usage against Candida infection and its removal for treatment if necessary. Because retained IUCD may cause serious clinical complications especially in pregnant women such as "fetal candidiasis" which may lead to miscarriage, premature labor or ectopic pregnancy. For these reasons, the possibility of candidiasis should be considered in patients wearing IUCD for a long period.
Related Concept Videos
Candidiasis
Cryptococcal Meningitis
Intrauterine Drug Delivery Systems
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Amebiasis
Trichomoniasis

