Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Metabonomics and its applications].

Jun Yang1, Shuo-Lin Song, Jose Castro-Perez

  • 1National Chromatographic R. & A. Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116011, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|April 30, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Establishment and application of a knowledge-directed pseudo-targeted analytical method for diabetic retinopathy].

Se pu = Chinese journal of chromatography·2026
Same author

Performance Characteristics of Zeno Trap Scanning DIA for Sensitive and Quantitative Proteomics at High Throughput.

Proteomics·2025
Same author

Multistage Tandem Mass Spectrometry Using an Electron-Activated Dissociation Device with a Linear Ion Trap and Structural Identification of Cardiolipins.

Analytical chemistry·2025
Same author

[Research progress of deep learning applications in mass spectrometry imaging data analysis].

Se pu = Chinese journal of chromatography·2024
Same author

[Preface for Special Issue of Environmental Exposomics and Human Health].

Se pu = Chinese journal of chromatography·2024
Same author

[New advances in exposomics-analysis methods and research paradigms based on chromatography-mass spectrometry].

Se pu = Chinese journal of chromatography·2024
Same journal

[Recent progress and policy recommendations for biomanufacturing technology in China].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2026
Same journal

[CRISPR/Cas9-mediated knockout of the <i>Soc</i> gene in T4 bacteriophage and mutant construction].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2026
Same journal

[High-throughput fluorescence-activated droplet sorting of polyethylene terephthalate hydrolases based on fluorescent nanoparticle biosensors].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2026
Same journal

[Machine learning-optimized solid-state fermentation of non-grain biomass for enhanced feed protein production].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2026
Same journal

[Growth and metabolic characteristics and kinetic modeling of MDCK adherent cells cultured in basket bioreactors].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2026
Same journal

[Metabolic engineering of <i>Saccharomyces cerevisiae</i> for <i>de novo</i> biosynthesis of gibberellin A<sub>3</sub>].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2026
See all related articles

Metabonomics, the study of metabolites, uses techniques like NMR and mass spectrometry for data acquisition and analysis. This field is crucial for disease diagnosis, drug development, and understanding biological systems.

Area of Science:

  • Metabolomics is an emerging scientific field focused on the comprehensive study of small molecules (metabolites) within biological systems.

Context:

  • Metabonomics involves analyzing the complete set of metabolites to understand physiological status.
  • Key techniques include Nuclear Magnetic Resonance (NMR), Gas Chromatography-Mass Spectrometry (GC/MS), and Liquid Chromatography-Mass Spectrometry (LC/MS/MS).
  • Data analysis commonly employs Principal Component Analysis (PCA), Partial Least Squares (PLS), and Artificial Neural Networks (ANN).

Purpose:

  • To introduce the fundamental concepts, characteristics, and historical development of metabonomics.
  • To summarize the advantages and disadvantages of prevalent data acquisition and analysis techniques.
  • To review recent advancements and diverse applications of metabonomics.

Summary:

  • The study outlines metabonomics, detailing its core principles and historical trajectory.

Related Experiment Videos

  • It critically evaluates common techniques for metabolite data acquisition (NMR, GC/MS, LC/MS/MS) and analysis (PCA, PLS, ANN), noting current limitations.
  • Recent applications in disease diagnosis, drug toxicity, plant, and microbial studies are highlighted, reflecting the field's rapid growth.

    • Impact:

    • Metabonomics is vital for identifying disease diagnostic biomarkers and understanding genome phenotype.
    • The field significantly benefits drug discovery, clinical diagnostics, and nutrition science.
    • Continued development, alongside functional genomics, promises substantial future contributions to biological and medical research.