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[Acardiac fetus--morphological and clinical aspects]
Ewa Czichos1, Michał Krekora, Andrzej Kałuzyński
1Zakład Patomorfologii Klinicznej Instytutu Centrum Zdrowia Matki Polki w łodzi., kierownik: prof. dr hab. med. A. Kulig; 2Klinika Medycyny Matczyno-Ptodowej Instytutu Centrum Zdrowia Matki Polki w Lodzi, kierownik: prof. dr hab. med. J. Wilczynski.
Summary
Twin reverse arterial perfusion (TRAP) sequence, a rare twin-to-twin transfusion syndrome complication, involves acardiac fetuses. Early diagnosis and intervention are crucial for the survival of the donor twin in these high-risk multiple pregnancies.
Area of Science:
- Perinatology
- Maternal-Fetal Medicine
- Congenital Malformations
Context:
- Multiple pregnancies present unique challenges in fetal development and maternal health.
- Twin-to-twin transfusion syndrome (TTTS) encompasses various complex placental vascular anastomoses.
- The twin reverse arterial perfusion (TRAP) sequence is a rare but severe form of TTTS.
Purpose:
- To describe the clinical presentation and outcomes of six cases of TRAP sequence.
- To highlight the rarity and specific challenges associated with acardiac twin malformations.
- To emphasize the importance of early diagnosis and management strategies for TRAP sequence.
Summary:
- Six cases of TRAP sequence, a complication of TTTS, involving acardiac fetuses were analyzed.
- Acardiac fetuses exhibit diverse morphologies, often with higher birth weight than the donor twin.
- Donor twins typically present with signs of circulatory overload, prematurity, intrauterine hypoxia, and anomalies.
Impact:
- This study underscores the critical need for early prenatal diagnosis of TRAP sequence.
- Prompt identification allows for timely intrauterine interventions to improve donor twin survival.
- Effective monitoring of the surviving donor twin post-diagnosis is essential for optimizing outcomes.