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Occupational asthma.

Cristina E Mapp1, Piera Boschetto, Piero Maestrelli

  • 1Section of Hygiene and Occupational Medicine, Department of Clinical and Experimental Medicine, University of Ferrara, Italy. mapp@unipd.it

American Journal of Respiratory and Critical Care Medicine
|April 30, 2005
PubMed
Summary

Occupational asthma, linked to workplace exposures, affects 9-15% of adult asthma cases. Early diagnosis and removal from exposure are key to better outcomes for this work-related respiratory condition.

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Area of Science:

  • Occupational Medicine
  • Pulmonology
  • Epidemiology

Background:

  • Workplace inhaled agents are a significant cause of adult asthma, accounting for 9-15% of cases in industrialized nations.
  • Occupational asthma (OA) encompasses immunologic, nonimmunologic, and work-aggravated forms, alongside variant syndromes.
  • Advances in environmental monitoring allow for the measurement of various workplace airborne agents.

Purpose of the Study:

  • To review the evidence and understanding of occupational asthma.
  • To discuss diagnostic approaches and management strategies for work-related asthma.
  • To highlight the importance of prevention and future research directions.

Main Methods:

  • Review of epidemiologic and clinical evidence on occupational asthma.

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  • Discussion of diagnostic criteria and environmental assessment techniques.
  • Exploration of host factors, genetic associations, and treatment outcomes.

    • Main Results:

    • Occupational factors contribute substantially to adult asthma prevalence.
    • Objective testing is crucial for early and reliable diagnosis of OA.
    • Worker removal from exposure and inhaled glucocorticoids improve outcomes.

    Conclusions:

    • Occupational asthma is a significant health issue requiring prompt diagnosis and management.
    • Further research into host factors and genetic predispositions is ongoing.
    • Implementing preventive strategies and evaluating their cost-effectiveness are essential for reducing OA incidence.