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Related Experiment Videos

Breathing pattern abnormalities in full term asphyxiated newborn infants.

P Sasidharan1

  • 1Department of Paediatrics, Medical College of Wisconsin, Milwaukee.

Archives of Disease in Childhood
|April 1, 1992
PubMed
Summary

Perinatal asphyxia significantly impacts full term infants, causing breathing pattern abnormalities in the first week of life. Studies show prolonged apnoea and periodic breathing are common in affected newborns.

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Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Perinatal Research

Background:

  • Perinatal asphyxia is a major cause of illness in full term infants.
  • Breathing pattern changes following perinatal asphyxia have not been well-documented.
  • Sudden infant death syndrome (SIDS) shares breathing abnormalities with asphyxiated infants.

Purpose of the Study:

  • To investigate and characterize breathing pattern abnormalities in full term infants during the first week after perinatal asphyxia.
  • To compare breathing patterns in asphyxiated infants with a healthy control group.

Main Methods:

  • Transthoracic impedance pneumocardiograms were used to monitor breathing patterns.
  • 16 full term infants with perinatal asphyxia were studied during their first week of life.
  • A control group of healthy infants was included for comparison.

Main Results:

  • Abnormal breathing patterns were observed in 69% of asphyxiated infants versus 13% in the control group.
  • Significant differences were found in prolonged apnoea, periodic breathing, and apnoea density.
  • These findings highlight distinct respiratory dysfunctions post-asphyxia.

Conclusions:

  • Perinatal asphyxia leads to significant and identifiable breathing pattern abnormalities in newborns.
  • These respiratory disturbances warrant further investigation and clinical attention.
  • The findings may offer insights into conditions like 'near miss' SIDS.

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